I see that this is an older thread, but I'll add my 2 cents in case anyone is interested.
I'm 53 and use Retin A for anti-aging, not acne. I started using it when it first came out about 25 years ago. I first started using it for acne, then stopped using it for a few years and have used it on and off for anti-aging ever since.
This might sound weird, but I use organic olive oil to cleanse my face and remove my makeup. I have found that this really combats the dryness and irritation I get with Retin-A. My skin is now very soft and has never looked better.
First I massage the olive oil into my skin and then let it sit for 30 seconds or so, then I tissue it off. I usually follow this by gently wiping my face with a warm, wet face cloth. If its a Retin-A night, I wait half an hour before applying the Retin-A. If its not a Retin-A night, I apply my moisturizer while my skin is slightly damp. In the mornings I sometimes use Acure Organics facial scrub or a gently cream cleanser or sometimes just plain water.
I started using this method of cleansing after a lot of trial and error. My skin would become so dry it was actually crusty and I would have to stop the Retin-A and then start over again a couple months later. I haven't had this problem since using the olive oil.
My dermatologist tells me to keep doing what I'm doing, and people always remark on how radiant and luminous my skin is. I'm 53 years old and I have no wrinkles.
Its very important to wait the half hour after washing your face before applying the Retin-A. At one point I used to mix my Retin-A with a basic face cream, but found my skin got much dryer and irritated. Retin-A and water is irritating, and there is water in face creams. If I want to use a moisturizer with my Retin-A, I now apply my Retin-A first, then wait half an hour for it to absorb completely and then apply my moisturizer. I find this to be much less irritating. I usually just use the Retin-A alone however.
I have other uses for the olive oil as well. About once a month, I saturate my hair with it and leave it on overnight. I put a towel over my pillow when I do this to protect my pillow. In the winter when my skin is very dry, I will rub the oil into my legs before getting in the shower and it really helps to combat dryness. I sometimes rub a little into my skin after my shower as well, but it can be oily so if I do this I use a towel to buff off the excess. I just do this on my legs and sometimes my arms, not my entire body. It makes my skin very soft and glowy.