Yes retin -a was the first topical they prescribed to me. It was ok, but because there were not enough results, I was switched to something else. I can cover my face pretty well with make up, and my acne has lessened substantially, but there isn't a time where i don't have at least 8 pimples on my face(and I'm not talking little bumps, I get big hard red bumps , I get them all over my cheeks, chin, forehead, upper lip, and sometimes on my nose). Plus, I have massive scarring from previous acne, so I NEVER go without make up. I have been on the quest for clear skin for 6yrs, 2 of which I was going to a derm constantly before I was given something that I had a severe allergic reaction to, so I just stopped going. I have found a few tings here and there that help alot, but with time they all stop working.