Something I found...Re Accutane (A mother questioning using this for her son)
"Possibly, but so many factors contribute to suicide, you can't exclusively blame a drug in every case. Still, the devastation to families affected by this medication is so horrific that it makes acne look beautiful.
Accutane and its generic, isotretinoin, can alter mood, and the manufacturer, Roche, openly shares this information. Other brand names include Amnesteem, Claravis and Sotret. These drugs, synthetic derivatives of vitamin A, can negatively impact brain chemicals such as dopamine and serotonin. An Accutane package insert warns of "depression, psychosis, and, rarely, suicidal ideation, suicide attempts and suicide."
Statistics show that between 1989 and 2003, there were 216 reported drug-linked suicides among U.S. teens under 18. Of these, 72 were linked to Accutane. The next highest number of drug-linked suicides in that period - 55 - involved Prozac (fluoxetine). The Food and Drug Administration Web site warns: "All patients treated with isotretinoin should be observed closely for symptoms of depression or suicidal thoughts, such as sad mood, irritability, acting on dangerous impulses, anger, loss of pleasure ... mood disturbance, psychosis or aggression.
I have had friends who have used Accutane and they had great results despite some of the side effects. As long as you are being monitored, are using contraception, I think that the positives can outweigh the negatives. I had a discussion with my derm about it and he feels that it can be great when kept under close eye. I am using clindamycin and I don't really care for it but I am going to try Differin ASAP. Good luck to you!