Originally Posted by SierraWren No, but my mother has.It made the lines between her nose and mouth("marionette lines") amazingly less deep, for about 4-5 months.She said it "piched a little, a few minutes" while injected and was then slowly massaged in(I don't know why they "massage" it in?)But she said it was a lot less painful than going to the dentist,and worth the 500-600 to her.(She had it done at her usual dermatologist's, didn't go through an advertisement. Maybe that's a little safer overall. Hmm, maybe they massage it so it won't turn out lumpy.