I had some Botox put in the outside corners of both my eyes when I got my upper right Bleph redone. It gave my eyes a more wide open look, but it also affected the left eye in that when I smiled it put wrinkles around the outside of my left brow bone which went away after a month. It looked weird and I was self conscious about it. My feeling is that if your muscles are frozen in one spot you may look unnatural. When the muscles do not work in conjunction with the other muscles it may have caused this unnatural look. I was asleep when this was done so I did not have to be aware of the needle going in my face. Would I do it again? Probably not. I hope I am making sense with my description. I hope this helps.
Joy